Radiation Biology

Radiation Oncology

Head of Department:
Prof. Dr. med. Rainer Fietkau

Radiation biology

Individualized cancer therapy is our main field of research. The following research groups are dealing with the different topics and we are studying here:

 

[Translate to en:] 2 metaphases stained by 3-color FiSH

We're studying:

  • patients' blood in order to analyse their individual radiation sensitivity and to be able to give a recommendation for the use of doses duiring radiation treatment.
  • Various methods to predict individual radiation sensitivity quickly and reliably.
  •  Prediction of radiation sensitivity by skin fibroblasts after bone marrow transplantation.
  • What significance does age have for radiation sensitivity
The inhibitor daprafenib in the foreground, bound to the b-Raf kinase(V600E)
  • Clinical and preclinical studies on the interactions of modern tumor therapeutics and ionizing radiation.
Tissue Micro Array stained by CD8 and FoxP3 - cytotoxic T cells and regulatory T cells
  • Importance of different inflammatory cells for the prognosis of patients with tumours.
  • Interactions of different inflammatory cells and their functional activity.
Phagocytosis by non-professional phagocytes
  • Both tumor cells and normal tissue cells can phagocytise other cells under appropriate conditions.
  • What are the mechanisms underlying non-professional phagocytosis.
  • What is the significance of non-professional phagocytosis in tumor tissue for the prognosis
The patient's quality of life and many of its influencing factors
  • The quality of life of young patients compared to older ones.
  • The influence of sport, religiousness and nutrition.
  • The influence of the family environment
Shakers

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Head of the research group
Go to the current publication

Go to the current publication

 

The way to the lab

Signage: Laboratory for molecular and cellular radiobiology (basement)

Location of the laboratory in the radiation department